Pyrazinamide
Pyrazinamide (PZA) is synthetic pyrazine analogue of nicotinamide. It is one of the key drugs included in therapeutic regimen to treat tuberculosis. TB is an […]
Pharmacology
Rifampicin
Rifampicin, also known as rifampin, is semi-synthetic derivative of rifamycin-B which is obtained from Streptomyces mediteranei. It is used to treat several types of bacterial […]
Leukotriene Modifiers
Leukotriene Modifiers are medicines used to manage allergic rhinitis or allergy and asthma. They are also known as antileukotriene or leukotriene antagonist. They entered clinical […]
Thiazolidinediones
Thiazolidinedione (TZDs) or glitazones are an important class of insulin sensitizers used in treatment of type 2 diabetes. Their introduction in the late 1990s was […]
Sulfonylurea
• Sulfonylurea are group of medicines used in treatment of type 2 diabetes. Sulfonylurea were discovered by chemist Marcel Jabon and coworkers in 1942, when […]
Sulfonamide
Sulfonamides are antimicrobial compound containing a sulfonamide group (SO2NH2). This group is also present in other non-antimicrobial compounds like antidiabetic sulfonylurea, thiazide diuretics, furosemide and […]
Metronidazole
Metronidazole is an antibiotic widely used in various bacterial and protozoal infections. It is a nitroimidazole derivative. It was first introduced in France in 1960 […]
Aminoglycosides
• Aminoglycoside are important group of antibiotics which act against gram-negative bacteria. The name ‘aminoglycoside’ is given as the structure consist of 2 amino sugars joined […]