Cell Wall Synthesis Inhibitors

January 17, 2023 Rima 0

Introduction Classification Beta-lactam antibiotics Figure- Structure of beta-lactam antibiotics (Source- Lippincott’s Illustrated Reviews, 6th edition) Glycopeptides Vancomycin, Daptomycin, Linezolid, Mupirocin, Retapamulin.  Bacterial cell wall and its […]

Carbachol Pharmacology

August 24, 2022 Rima 0

Carbachol is ester of choline with carbamic acid which shows cholinergic (both muscarinic and nicotinic) actions. Carbachol is also known as carbamylcholine. It was discovered […]

Felbamate Pharmacology

August 10, 2022 Rima 0

Felbamate belongs to class of drug called anticonvulsants or anti-epileptics. Felbamate is available in USA and some European countries. Not available in Canada, UK and […]

Acarbose

July 28, 2022 Rima 0

Acarbose belongs to group of drugs called alpha glucosidase inhibitors which are oral hypoglycemic agents. Acarbose is one of the two approved alpha glucosidase inhibitors. […]

Polymyxins Pharmacology

July 11, 2022 Rima 0

Polymyxins are group of antibiotics having bactericidal activity against gram negative bacteria. There are two clinically available polymyxins- polymyxin B and colistin (polymyxin E). Polymyxins […]

Leflunomide Pharmacology

June 21, 2022 Rima 0

Leflunomide belongs to class of drug called DMARDs (Disease Modifying Anti- Rheumatic Drugs). It is non-biological novel isoxazole derivative. Leflunomide got its FDA approval for […]

Entecavir Pharmacology

June 17, 2022 Rima 0

Entecavir is guanosine nucleoside analogue used as anti- hepatitis B drug. Entecavir got its FDA approval in March 2005. It is included in World Health […]

Tobramycin Pharmacology

June 14, 2022 Rima 0

Tobramycin belongs to class of drug called aminoglycoside antibiotics. Tobramycin is derived from Streptomyces tenebrarius. It was approved by FDA in 1975. Tobramycin contains 4,6-disubstituted 2-deoxystreptamine (DOS) ring. […]

Orlistat Pharmacology

June 8, 2022 Rima 0

Orlistat is lipase inhibitor used in treatment of obesity. Currently, orlistat is the only available agent of anti- obesity drugs of class lipase inhibitor. It […]

Dipeptidyl peptidase-4 inhibitors

June 6, 2022 Rima 0

Dipeptidyl peptidase-4 inhibitors which are also known as gliptins are oral anti- hyperglycemic medications used in treating type 2 diabetes mellitus. Dipeptidyl peptidase-4 inhibitors are […]