Cell Wall Synthesis Inhibitors

January 17, 2023 Rima 0

Introduction Classification Beta-lactam antibiotics Figure- Structure of beta-lactam antibiotics (Source- Lippincott’s Illustrated Reviews, 6th edition) Glycopeptides Vancomycin, Daptomycin, Linezolid, Mupirocin, Retapamulin.  Bacterial cell wall and its […]

Daptomycin

August 24, 2021 Rima 0

Daptomycin is cyclic lipopeptide antibiotic which is derived from Streptomyces roseosporus.  It was first discovered in early 1980s by scientists of Eli Lillly. Early work on […]

Nitrofurantoin Pharmacology

June 19, 2021 Rima 0

Nitrofurantoin is synthetic nitrofuran used to prevent and treat UTI (Urinary Tract Infections). It was approved by FDA in 1953. It is included in World […]

Carbapenems

April 23, 2021 Rima 0

Carbapenems are beta- lactam antibiotics which have broader spectrum of activity and great potency compared to other beta-lactam antibiotics. They are closely related to penicillin. […]

Erythromycin

August 17, 2020 Rima 0

Erythromycin is an antibiotic used to treat various bacterial infections. It is derived from the fungus Streptomyces erythreus. Erythromycin belongs to family of macrolide antibiotics […]

Tetracyclines

May 18, 2020 Rima 0

Tetracyclines are broad spectrum antibiotics, discovered in the 1940s. Chlortetracycline is the first tetracycline to be identified. It was isolated from Streptomyces aureofaciens. Tetracyclines are […]

Chloramphenicol

May 15, 2020 Rima 0

Chloramphenicol Chloramphenicol is broad spectrum antibiotic derived from Streptomyces venezuelae. It was introduced into clinical practice in 1949. Chloramphenicol was the first antibiotic to be […]