hypertension

Prazosin

May 18, 2021 Rima 0

Prazosin is selective α-1 blocker which is used to treat hypertension. It got its FDA approval for it’s medical use in 1988. Chemically, it is […]

Hydralazine

October 31, 2020 Rima 0

Hydralazine is a direct arterial vasodilator and is used for treatment of hypertension and heart failure. It is used as anti-hypertensive agent since 1950s. It […]

Aliskiren

October 14, 2020 Rima 0

Aliskiren is a first drug of the class direct renin inhibitors (DRI). It is only direct renin inhibitor approved for the treatment of hypertension. Hypertension […]

Reserpine

July 2, 2020 Rima 0

Reserpine is a Rauwolfia alkaloid obtained from root of the plant Rauwolfia serpentina or Sarpagandha. Reserpine was used in India from ancient times for conditions like […]

Spironolactone

June 24, 2020 Rima 0

Spironolactone is potassium-sparing diuretic which is structurally similar to aldosterone. It was discovered in 1957 and introduced in 1959. Spironlactone is on the WHO’s (World […]

Angiotensin Receptor Blocker

June 10, 2020 Rima 0

Angiotensin II receptor blocker (ARBs) are one of the most commonly used drugs for hypertension. They are often prescribed as first-line antihypertensive agents in patients […]

ACE Inhibitors

June 5, 2020 Rima 0

ACE (Angiotensin Converting Enzyme) inhibitors or ACE-I are among the most widely used cardiovascular medicines. Their introduction in 1980s improve the management of hypertension. Captopril […]