Bendamustine Pharmacology

May 24, 2022 Rima 0

Bendamustine is unique structured cytotoxic alkylating agent. Chemically, it is 4-[5-[bis(2-chloroethyl)amino]-1-methyl-benzoimidazol-2-yl] butyric acid hydrochloride. It is a nitrogen mustard drug. Bendamustine consist of three major components in its […]

Ifosfamide Pharmacology

November 29, 2021 Rima 0

Ifosfamide is analog of cyclophosphamide. It is cytotoxic, antineoplastic agent and belongs to class of oxazaphosphorine alkylating agents.  It is commonly used alkylating agent in […]

Carmustine

December 29, 2020 Rima 0

Carmustine is an alkylating agent used as anti-neoplastic drug. It belongs to class of nitrogen mustard. Carmustine is β-chloro-nitrosourea compound (BCNU). Uses of carmustine Used […]

Chlorambucil

December 28, 2020 Rima 0

Chlorambucil is an aromatic nitrogen mustard derivative. It is a bifunctional alkylating agent and is commonly used chemotherapeutic agent. It was first synthesized by Everett […]

Cyclophosphamide

December 26, 2020 Rima 0

Cyclophosphamide is most used alkylating agent. It is an alkylating agent with cytotoxic and immunosuppressive properties. It is chemotherapeutic agent used to treat different kinds […]