Carmustine
Carmustine is an alkylating agent used as anti-neoplastic drug. It belongs to class of nitrogen mustard. Carmustine is β-chloro-nitrosourea compound (BCNU). Uses of carmustine Used […]
Carmustine is an alkylating agent used as anti-neoplastic drug. It belongs to class of nitrogen mustard. Carmustine is β-chloro-nitrosourea compound (BCNU). Uses of carmustine Used […]
Chlorambucil is an aromatic nitrogen mustard derivative. It is a bifunctional alkylating agent and is commonly used chemotherapeutic agent. It was first synthesized by Everett […]
Alkylating agents are among the oldest and useful anti-neoplastic drugs. They are cytotoxic drugs and hence, act directly on cells. Before introduction of alkylating agents […]
Cyclophosphamide is most used alkylating agent. It is an alkylating agent with cytotoxic and immunosuppressive properties. It is chemotherapeutic agent used to treat different kinds […]
Paclitaxel is natural product with antitumor activity. It is isolated from bark of Western Yew tree (Taxus brevifolia). Paclitaxel is microtubule inhibitor. It is […]
Camptothecin (CPT) are cytotoxic quinoline alkaloids which are originally isolated from Chinese tree Camptotheca (Camptotheca acuminata). Camptothecin analogues like topotecan and irinotecan are used to […]
Fibric acid derivatives (Fibrates) Fibric Acid Derivatives are derivatives of fibric acid. They are used to lower blood triglyceride level. The first fibrate discovered was […]
Bile acid sequestering agents Bile acid sequestering agent are hypolipidemic agents used to lower LDL cholesterol. Cholestyramine and colestipol are two established bile acid sequestrants […]
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