Articles by Rima
Azathioprine
Azathioprine is imidazolyl derivative of 6-mercaptopurine and is a purine antimetabolite. It was first agent to be used in organ transplantation. However, discovery of ciclosporin […]
Mycophenolate mofetil Pharmacology
Mycophenolate mofetil is 2-morpholinoethyl ester of mycophenolic acid (MPA). It is prodrug and is also known as cellcept or MMF. Mycophenolic acid is antibiotic obtained […]
Cyclosporine
Cyclosporine is lipophilic cyclic polypeptide which is extracted from the soil fungus Beauveria nivea. It acts as calcineurin inhibitor and has immunosuppressive properties. It was […]
Everolimus Pharmacology
Everolimus is macrolide derivative and belongs to class of mTOR (mammalian target of Rapamycin) inhibitor. Its indication includes immunosuppressant and oncological indications. It is derivative […]
Tacrolimus
Tacrolimus is macrolide antibiotic and is commonly used as immunosuppressive agent. It was discovered in 1984 in fermentation broth of Japanese sample soil containing bacteria Streptomyces […]
Fluconazole- an anti-fungal agent
Fluconazole is member of triazole antifungal agents, one of the commonly used antifungal agents. It is the first member of triazole class of antifungal agents […]
Posaconazole
Posaconazole is triazole antifungal agent. It is chemically related to itraconazole. It is a second generation, synthetic triazole and has broad spectrum antifungal agent. Posaconazole […]
Voriconazole
Voriconazole is synthetic, second- generation, triazole antifungal agent. Its structure is like fluconazole, but it has broad spectrum and expanded activity. It was approved by […]