Bleomycin

December 31, 2020 Rima 0

Bleomycin is a family of natural glycopeptidic antibiotics fermented by Streptomyces verticillus. It is used as anti-neoplastic agent. It is available as generic medicine and […]

Carmustine

December 29, 2020 Rima 0

Carmustine is an alkylating agent used as anti-neoplastic drug. It belongs to class of nitrogen mustard. Carmustine is β-chloro-nitrosourea compound (BCNU). Uses of carmustine Used […]

Chlorambucil

December 28, 2020 Rima 0

Chlorambucil is an aromatic nitrogen mustard derivative. It is a bifunctional alkylating agent and is commonly used chemotherapeutic agent. It was first synthesized by Everett […]

Alkylating agents

December 27, 2020 Rima 0

Alkylating agents are among the oldest and useful anti-neoplastic drugs. They are cytotoxic drugs and hence, act directly on cells. Before introduction of alkylating agents […]

Cyclophosphamide

December 26, 2020 Rima 0

Cyclophosphamide is most used alkylating agent. It is an alkylating agent with cytotoxic and immunosuppressive properties. It is chemotherapeutic agent used to treat different kinds […]

Etoposide

December 23, 2020 Rima 0

Etoposide is semi-synthetic derivative of podophyllotoxin obtained from plant Podophyllum peltatum. It is an anti-neoplastic agent used to treat different kinds of cancer. Etoposide is […]

Flutamide

December 22, 2020 Rima 0

Flutamide is non-steroidal anti-androgen compound used to treat prostate cancer. It is a toluidine derivative. Prostate cancer is most common type of cancer. Some prostate […]

Paclitaxel

December 21, 2020 Rima 0

Paclitaxel is natural product with antitumor activity. It is isolated from bark of Western Yew tree (Taxus brevifolia). Paclitaxel is microtubule inhibitor.   It is […]

Camptothecin Analogues

December 19, 2020 Rima 0

Camptothecin (CPT) are cytotoxic quinoline alkaloids which are originally isolated from Chinese tree Camptotheca (Camptotheca acuminata). Camptothecin analogues like topotecan and irinotecan are used to […]

Fibric Acid Derivatives

December 18, 2020 Rima 0

Fibric acid derivatives (Fibrates) Fibric Acid Derivatives are derivatives of fibric acid. They are used to lower blood triglyceride level. The first fibrate discovered was […]