Vinca alkaloids

December 12, 2020 Rima 0

Vinca alkaloids are isolated from periwinkle plant (Vinca rosea, Catharanthus rosens). They possess anti-mitotic and anti-microtubule properties. Vinca alkaloids are structurally similar but have different […]

Statins

December 8, 2020 Rima 0

Statins or HMG CoA reductase inhibitors are lipid lowering agents and are among the most widely used drugs in cardiovascular pharmacology. Some commonly used statins […]

Celecoxib

November 7, 2020 Rima 0

Celecoxib is non-steroidal anti-inflammatory agent (NSAIDs) used to treat pain and inflammation. Most of the NSAIDs used including aspirin, ibuprofen and indomethacin are associated with […]

Ibuprofen

November 6, 2020 Rima 0

Ibuprofen is first of the propionic acid derivative introduced in 1959 in United Kingdom. It is one of the most used NSAIDs and available as […]

Hydralazine

October 31, 2020 Rima 0

Hydralazine is a direct arterial vasodilator and is used for treatment of hypertension and heart failure. It is used as anti-hypertensive agent since 1950s. It […]

SGLT-2 Inhibitors

October 30, 2020 Rima 0

What are SGLT-2 inhibitors? SGLT-2 Inhibitors or sodium- glucose co-transporter 2 inhibitors are class of medications used to lower high blood glucose level in type […]

Endothelin Receptor Antagonist

October 23, 2020 Rima 0

Endothelin receptor antagonist are pharmacological agents that block endothelin receptors. They are used to treat pulmonary arterial hypertension (PAH). They were discovered in late 1980s. […]

Aliskiren

October 14, 2020 Rima 0

Aliskiren is a first drug of the class direct renin inhibitors (DRI). It is only direct renin inhibitor approved for the treatment of hypertension. Hypertension […]

Phenoxybenzamine

September 20, 2020 Rima 0

Phenoxybenzamine is non-competitive antagonist of alpha (alpha-1 and alpha-2) receptor. It causes irreversible blockade of these receptors. Phenoxybenzamine is classified chemically as haloalkylamine. It got […]