Cyclophosphamide

December 26, 2020 Rima 0

Cyclophosphamide is most used alkylating agent. It is an alkylating agent with cytotoxic and immunosuppressive properties. It is chemotherapeutic agent used to treat different kinds […]

Etoposide

December 23, 2020 Rima 0

Etoposide is semi-synthetic derivative of podophyllotoxin obtained from plant Podophyllum peltatum. It is an anti-neoplastic agent used to treat different kinds of cancer. Etoposide is […]

Flutamide

December 22, 2020 Rima 0

Flutamide is non-steroidal anti-androgen compound used to treat prostate cancer. It is a toluidine derivative. Prostate cancer is most common type of cancer. Some prostate […]

Paclitaxel

December 21, 2020 Rima 0

Paclitaxel is natural product with antitumor activity. It is isolated from bark of Western Yew tree (Taxus brevifolia). Paclitaxel is microtubule inhibitor.   It is […]

Camptothecin Analogues

December 19, 2020 Rima 0

Camptothecin (CPT) are cytotoxic quinoline alkaloids which are originally isolated from Chinese tree Camptotheca (Camptotheca acuminata). Camptothecin analogues like topotecan and irinotecan are used to […]

Fibric Acid Derivatives

December 18, 2020 Rima 0

Fibric acid derivatives (Fibrates) Fibric Acid Derivatives are derivatives of fibric acid. They are used to lower blood triglyceride level. The first fibrate discovered was […]

Bile Acid Sequestering Agents

December 18, 2020 Rima 0

Bile acid sequestering agents Bile acid sequestering agent are hypolipidemic agents used to lower LDL cholesterol. Cholestyramine and colestipol are two established bile acid sequestrants […]

Vinca alkaloids

December 12, 2020 Rima 0

Vinca alkaloids are isolated from periwinkle plant (Vinca rosea, Catharanthus rosens). They possess anti-mitotic and anti-microtubule properties. Vinca alkaloids are structurally similar but have different […]

Statins

December 8, 2020 Rima 0

Statins or HMG CoA reductase inhibitors are lipid lowering agents and are among the most widely used drugs in cardiovascular pharmacology. Some commonly used statins […]

Celecoxib

November 7, 2020 Rima 0

Celecoxib is non-steroidal anti-inflammatory agent (NSAIDs) used to treat pain and inflammation. Most of the NSAIDs used including aspirin, ibuprofen and indomethacin are associated with […]