Cyclosporine

July 29, 2021 Rima 0

Cyclosporine is lipophilic cyclic polypeptide which is extracted from the soil fungus Beauveria nivea. It acts as calcineurin inhibitor and has immunosuppressive properties. It was […]

Everolimus Pharmacology

July 28, 2021 Rima 0

Everolimus is macrolide derivative and belongs to class of mTOR (mammalian target of Rapamycin) inhibitor. Its indication includes immunosuppressant and oncological indications.  It is derivative […]

Sirolimus

July 27, 2021 Rima 0

Sirolimus is macrolide antibiotic obtained from soil mold Streptomyces hygroscopicus. It is used for its immunosuppressant properties.  Sirolimus is like tacrolimus in structure but have different […]

Tacrolimus

July 26, 2021 Rima 0

Tacrolimus is macrolide antibiotic and is commonly used as immunosuppressive agent. It was discovered in 1984 in fermentation broth of Japanese sample soil containing bacteria Streptomyces […]

Posaconazole

July 22, 2021 Rima 0

Posaconazole is triazole antifungal agent. It is chemically related to itraconazole. It is a second generation, synthetic triazole and has broad spectrum antifungal agent.  Posaconazole […]

Voriconazole

July 21, 2021 Rima 0

Voriconazole is synthetic, second- generation, triazole antifungal agent. Its structure is like fluconazole, but it has broad spectrum and expanded activity.  It was approved by […]

Itraconazole

July 20, 2021 Rima 0

Itraconazole is broad spectrum antifungal agent. It is a synthetic triazole and has activity like ketoconazole. Other triazole antifungals available in medical field includes fluconazole, […]

Galantamine

July 19, 2021 Rima 0

Galantamine is oral acetylcholinesterase (AChE) inhibitor. Acetylcholinesterase is enzyme involved in hydrolysis of acetylcholine.  Galantamine belongs to isoquinoline alkaloid family. It was discovered and isolated […]