Azathioprine
Azathioprine is imidazolyl derivative of 6-mercaptopurine and is a purine antimetabolite. It was first agent to be used in organ transplantation. However, discovery of ciclosporin […]
immunosuppressant
Cyclosporine
Cyclosporine is lipophilic cyclic polypeptide which is extracted from the soil fungus Beauveria nivea. It acts as calcineurin inhibitor and has immunosuppressive properties. It was […]
Everolimus Pharmacology
Everolimus is macrolide derivative and belongs to class of mTOR (mammalian target of Rapamycin) inhibitor. Its indication includes immunosuppressant and oncological indications. It is derivative […]
Tacrolimus
Tacrolimus is macrolide antibiotic and is commonly used as immunosuppressive agent. It was discovered in 1984 in fermentation broth of Japanese sample soil containing bacteria Streptomyces […]
Methotrexate
Methotrexate is chemotherapeutic agent and immunosuppressant used to treat various cancers and autoimmune diseases. It is an antimetabolite (chemical agent which are structurally like metabolites […]