cancer
Paclitaxel
Paclitaxel is natural product with antitumor activity. It is isolated from bark of Western Yew tree (Taxus brevifolia). Paclitaxel is microtubule inhibitor. It is […]
Camptothecin Analogues
Camptothecin (CPT) are cytotoxic quinoline alkaloids which are originally isolated from Chinese tree Camptotheca (Camptotheca acuminata). Camptothecin analogues like topotecan and irinotecan are used to […]
Vinca alkaloids
Vinca alkaloids are isolated from periwinkle plant (Vinca rosea, Catharanthus rosens). They possess anti-mitotic and anti-microtubule properties. Vinca alkaloids are structurally similar but have different […]
Methotrexate
Methotrexate is chemotherapeutic agent and immunosuppressant used to treat various cancers and autoimmune diseases. It is an antimetabolite (chemical agent which are structurally like metabolites […]
Dexamethasone
Dexamethasone is a synthetic corticosteroid used from many years in clinical practice for its anti-inflammatory, anti-allergic and immunosuppressive properties. Dexamethasone was first synthesized in 1957 […]