Etoposide

December 23, 2020 Rima 0

Etoposide is semi-synthetic derivative of podophyllotoxin obtained from plant Podophyllum peltatum. It is an anti-neoplastic agent used to treat different kinds of cancer. Etoposide is […]

Paclitaxel

December 21, 2020 Rima 0

Paclitaxel is natural product with antitumor activity. It is isolated from bark of Western Yew tree (Taxus brevifolia). Paclitaxel is microtubule inhibitor.   It is […]

Camptothecin Analogues

December 19, 2020 Rima 0

Camptothecin (CPT) are cytotoxic quinoline alkaloids which are originally isolated from Chinese tree Camptotheca (Camptotheca acuminata). Camptothecin analogues like topotecan and irinotecan are used to […]

Vinca alkaloids

December 12, 2020 Rima 0

Vinca alkaloids are isolated from periwinkle plant (Vinca rosea, Catharanthus rosens). They possess anti-mitotic and anti-microtubule properties. Vinca alkaloids are structurally similar but have different […]

Methotrexate

September 13, 2020 Rima 0

Methotrexate is chemotherapeutic agent and immunosuppressant used to treat various cancers and autoimmune diseases. It is an antimetabolite (chemical agent which are structurally like metabolites […]

Dexamethasone

June 17, 2020 Rima 2

Dexamethasone is a synthetic corticosteroid used from many years in clinical practice for its anti-inflammatory, anti-allergic and immunosuppressive properties. Dexamethasone was first synthesized in 1957 […]