Li- Fraumeni Syndrome
Li- Fraumeni syndrome also known as sarcoma, breast, leukemia, and adrenal gland (SBLA) cancer syndrome, is a rare inherited autosomal-dominant disorder. It is associated with […]
Ifosfamide Pharmacology
Ifosfamide is analog of cyclophosphamide. It is cytotoxic, antineoplastic agent and belongs to class of oxazaphosphorine alkylating agents. It is commonly used alkylating agent in […]
Mechlorethamine Pharmacology
Mechlorethamine is first nitrogen mustard used in cancer therapy. It is also known as mustine or chlormethine. It was used as war gas before and […]
Diabetes mellitus vs Diabetes Insipidus
Diabetes mellitus (DM) and diabetes insipidus (DI) are two different medical condition having the same first word of their name ‘diabetes’. They may have some similar features but […]
Mesothelioma
Mesothelioma is the cancer of mesothelial cells. These cells form the lining layer of viscera like in pleura, peritoneum, and tunica vaginalis. The most common […]
eIF2 (eukaryotic initiation factor 2)
Protein synthesis (translation) in eukaryotes begins after methionyl charged initiator t-RNA is delivered to ribosomes by eIF2 (eukaryotic initiation factor 2). eIF2 is one among […]
eIF4F (eukaryotic initiation factor 4F)
Eukaryotic initiation factor 4F or eIF4F play important role in regulating initiation of translation. There are many different eukaryotic initiation factors which play important role in […]
Fosfomycin
Fosfomycin is synthetic derivative of phosphonic acid. It is broad spectrum antibiotic which is produced from organism Streptomyces fradiae. It is also produced synthetically. Fosfomycin was […]
Telavancin
Telavancin is semisynthetic lipoglycopeptide derivative of vancomycin with a hydrophobic side chain attached to vancosamine sugar. It was discovered in 2000 and is first marketed […]