Cell Wall Synthesis Inhibitors

January 17, 2023 Rima 0

Introduction Classification Beta-lactam antibiotics Figure- Structure of beta-lactam antibiotics (Source- Lippincott’s Illustrated Reviews, 6th edition) Glycopeptides Vancomycin, Daptomycin, Linezolid, Mupirocin, Retapamulin.  Bacterial cell wall and its […]

Leflunomide Pharmacology

June 21, 2022 Rima 0

Leflunomide belongs to class of drug called DMARDs (Disease Modifying Anti- Rheumatic Drugs). It is non-biological novel isoxazole derivative. Leflunomide got its FDA approval for […]

Ranitidine

May 16, 2022 Rima 0

On April 1, 2020, FDA announced that it is requesting manufacturers to withdraw all prescription and over the counter (OTC) ranitidine drugs from the market […]

Screening of Anti-depressants

February 21, 2022 Rima 0

Depression is one of the common psychiatric diseases which is characterized by various symptoms including low self-esteem, feeling of hopelessness and worthlessness, depressed mood, and […]

Allopurinol

August 17, 2021 Rima 0

Allopurinol is xanthine oxidase inhibitor used in treating gout. Chemically, it is 4-hydroxy-pyrazolo 3, 4 d-pyrimidine. It is an analogue of hypoxanthine.  It was approved […]

Aripiprazole

April 8, 2021 Rima 0

Aripiprazole is a 2nd generation antipsychotic which was approved by FDA in 2002 for treatment of schizophrenia. Some researchers also consider aripiprazole as 3rd generation […]

Nuclear Receptors

March 14, 2021 Rima 0

Nuclear receptors (NRs) are a class of proteins which respond to intra and extracellular signal carried by steroid or thyroid hormones leading to regulation of […]

Flutamide

December 22, 2020 Rima 0

Flutamide is non-steroidal anti-androgen compound used to treat prostate cancer. It is a toluidine derivative. Prostate cancer is most common type of cancer. Some prostate […]